Free Pharmacy Books

Patient Compliance: Sweetening the Pill

2010-02-09T08:04:00.001+02:00

Vast global resources are ploughed into the delivery of treatment interventions ranging from diet and lifestyle advice through to complex surgery. In all cases, whatever the intervention, unless the recipient is engaged with the process and understands why the intervention has been offered and the part they play in its success, compliance will be an issue. Even where the individual does engage and understand, he or she may choose, in the light of that knowledge, not to comply. This book aims to explore the key factors which drive compliance and the part that healthcare professionals can play in improving this, with the key underlying goal of improving public health in its broadest sense.

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The Textbook of Pharmaceutical Medicine

2010-02-09T08:02:00.000+02:00

John P. Griffin, "The Textbook of Pharmaceutical Medicine"
BMJ Books / Wiley-Blackwell | 2009 | ISBN: 1405180358 | 776 pages | PDF | 3,8 MB

The Textbook of Pharmaceutical Medicine is a standard reference for all those working in pharmaceutical medicine and the recognised text for the UK Faculty of Pharmaceutical Medicine Diploma. This is a comprehensive volume covering the processes by which medicines are developed, tested and approved. Regulations for drug development in the UK, EU, USA, Australia and Japan are discussed, providing relevant information for drug approval in the main continents where new drugs are developed.

The chapters are written by leading academics, medical directors and lawyers, providing authoritative and in-depth information for trainees on the Faculty course, and for physicians working in the pharmaceutical industry. As well as thorough updating of the regulatory chapters, the 6th edition includes chapters on these vital new areas:
Paediatric regulation
Ethics
Due diligence and the pharmaceutical physician

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Wilson & Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry

2010-02-09T08:01:00.000+02:00

Oregon State Univ., Corvallis. Blends the chemical and pharmaceutical principles necessary for understanding structure-activity relationships and molecular mechanisms of drug action. Offers new information on emerging trends and advances and the challenges posed by new diseases. Features a new chapter on combinatorial chemistry.

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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition: (Six-Volume Set)

2010-02-09T07:57:00.000+02:00

Sarfaraz K. Niazi, "Handbook of Pharmaceutical Manufacturing Formulations, Second Edition: (Six-Volume Set)"
Informa Healthcare | 2009 | ISBN: 1420081063, 1420081306, 1420081284, 1420081268, 1420081233, 1420081187, 1420081160 | 2094 pages | PDF | 16,2 MB

Includes:
Volume 1: Compressed Solid Products
Volume 2: Uncompressed Solid Products
Volume 3: Liquid Products
Volume 4: Semisolid Products
Volume 5: Over-the-Counter Products
Volume 6: Sterile Products

An authoritative and practical guide to the art and science of formulating drugs.

With thoroughly revised and expanded content, this Second Edition six-volume set compiles volumes from FDA New Drug Applications, patent applications, and other sources of generic and proprietary formulations to cover the broad spectrum of issues concerning drug manufacturing.

A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this set is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent.

As the largest reference on pharmaceutical formulations, this handbook also provides guidelines on how to file aNDAs in the shortest possible time, helping pharmaceutical companies to cut costs in the areas of pharmaceutical research and development.

Divided conveniently into two parts—regulatory and manufacturing guidelines, and formulations—each volume in the set covers:

* cGMP compliance
* pre-approval inspections
* stability and bioequivalence testing
* packaging commodity development
* common difficulties in formulating drugs
* changes to aNDAs

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Pharmaceuticals-where's the Brand Logic?: Branding Lessons and Strategy

2010-02-09T07:52:00.000+02:00

Giles D. Moss, "Pharmaceuticals-where's the Brand Logic?: Branding Lessons and Strategy"
Informa Healthcare | 2007 | ISBN: 0789032589, 0789032597 | 248 pages | PDF | 10,8 MB

Insights and analysis that challenge current thought on consumer branding theory and strategy

Pharmaceutical companies need to go beyond simply relying on strong sales forces and innovative research and development to succeed. Effective branding strategy is essential. Pharmaceuticals--Where's the Brand Logic?: Branding Lessons and Strategy discusses in detail the application of current consumer branding theory to pharmaceutical marketing. This comprehensive book pulls information from fast moving consumer goods (FMCG) research and brand theory and applies it to the pharmaceutical world. It looks at branding on multiple levels within the pharmaceutical industry, including the industry brand, the corporate brand, the franchise brand, and the global and local product brand. Practical strategies are extensively explained and future challenges facing the pharmaceutical industry are explored, all geared to help any pharmaceutical professional to successfully market their brand.

Pharmaceuticals--Where's the Brand Logic?: Branding Lessons and Strategy may well become a daily reference for anyone in the industry, providing in a single volume a framework for the organization of a brand portfolio for any pharmaceutical company. This unique resource challenges traditional thought about the concept of branding in the pharmaceutical industry, examining several of the most difficult branding theory issues. This helpful guide provides several figures to fully explain data.

Topics in Pharmaceuticals--Where's the Brand Logic?: Branding Lessons and Strategy include:

What is branding
How is branding applied to the FMCG and pharmaceutical industries
Corporate brands--and how they can be leveraged
Franchise branding as a business strategy
Developing and sustaining pharmaceutical brands over time
Saving the credibility of the pharmaceutical industry
Changing the pharmaceutical business model to use branding as a strategic tool
And much, more

Pharmaceuticals--Where's the Brand Logic?: Branding Lessons and Strategy provides the information and tools to help gain the competitive edge in a tough marketplace. This is an invaluable resource for anyone in the global pharmaceutical industry, including marketing personnel, senior management, general managers, strategy groups, and training departments.

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Martindale: The Complete Drug Reference - 35th Edition

2009-10-16T19:04:00.000+02:00

Sean C. Sweetman, Paul S Blake, Julie M. McGlashan, Gail C. Neatherco, «Martindale: The Complete Drug Reference - 35th Edition»
Pharmaceutical Press ISBN 085369687X 35th Edition - 2007 Format ISO 3322 Pages 470,0 Mb

Martindale: The complete drug reference has been continuously expanded since it was first published in 1883. In this 35th edition, every entry hasbeen checked and updated where necessary. The extra information, and largertext size chosen to make the books easier to read, is contained in a new cased two-volume format. The first volume contains the preface and the drugmonographs, while the second volume holds all proprietary preparations and the index, as well as manufacturers' contact information

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British National Formulary for Children 2009

2009-10-16T18:56:00.000+02:00

British National Formulary for Children 2009
By Paediatric Formulary Committee
Publisher: Pharmaceutical Press 2009 974 Pages ISBN: 0853698473 PDF 6.11 MB

“

BNF for Children (BNFC) provides essential practical information to all healthcare professionals involved in the prescribing, dispensing, monitoring and administration of medicines to children. The resource addresses a significant knowledge gap in many areas of paediatric practice by providing practical information on the use of medicines in children of all ages from birth to adolescence.

”

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Recombinant Antibodies for Immunotherapy

2009-10-16T18:50:00.000+02:00

Melvyn Little PhD, "Recombinant Antibodies for Immunotherapy"
Cambridge University Press 2009 ISBN: 0521887321 440 pages PDF 3,8 MB

Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, "arming" mAbs, novel alternative Ab constructs, increasing half-lives, alternative concepts employing non-immunoglobulin scaffolds, novel therapeutic approaches, a market analysis of therapeutic mAbs, and future developments in the field. The concepts and technologies are illustrated by examples of recombinant antibodies being used in the clinic or in development. This book will appeal to both newcomers and experienced scientists in the field, biology and biotechnology students, research and development departments in the pharmaceutical industry, medical researchers, clinicians, and biotechnology investors.

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Chirality in Drug Research (repost)

2009-10-16T18:47:00.001+02:00

Eric Francotte (Editor), Raimund Mannhold, Hugo Kubinyi "Chirality in Drug Research"
Wiley-VCH English 2007-01-02 ISBN: 3527310762 370 pages PDF 3,4 MB

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals.
The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data.

In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions.

With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.

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The British Pharmacopoeia 2009(PDF)

2009-10-16T18:24:00.000+02:00

The British Pharmacopoeia" ("BP") 2009
Stationery Office Books ISBN: 011322799X 95 MB 3500 pages PDF Rapidshare

Product Description
"The British Pharmacopoeia" ("BP") 2009 is the authoritative, current collection of standards for UK medicinal substances and the official source of all UK pharmaceutical quality standards. It is an essential reference for anyone involved in pharmaceutical research, development, manufacture and testing, and plays a vital role in ensuring that all medicinal substances on the UK market meet standards of safety, quality and efficacy.The "BP" comprises monographs, which set out the mandatory standards for active substances, excipients and formulated preparations, together with supporting General Notices, Appendices (test methods, reagents, etc) and Reference Spectra. Detailed information and guidance on various aspects of current pharmacopoeial policy and practice are provided in the Supplementary Chapters of the "BP".The "BP" is supplied in a variety of formats designed for ease of use and a wide range of applications. The hard copy edition comprises a five-volume boxed set containing the "BP" in four volumes and the "BP" (Veterinary) volume, plus single user access to the "BP" Online, the dedicated BP website. The online format is easy to network, allowing access for a specified number of users or across an entire organisation site.Following registration - using the ID code supplied with the hard copy - customers will be granted a single user licence to access BP on-line and will have the option to receive the CD-ROM, which contains the whole of the current "British Pharmacopoeia".It is effective as of 1 January 2009. It includes: a significant number of new UK monographs; all "European Pharmacopoeia 6th Edition" material up to and including "Supplement 6.2" integrated into the text of "BP 2009"; new and revised monographs for Complementary, Herbal and Homoeopathic medicines with their own section in Volume III; and networking with full technical support from TSO, the publisher of the "BP". The on-line version delivers the complete text of the "British Pharmacopoeia and European Pharmacopoeia" standards to your PC. The new features include an alphabetical index, user-friendly search interface design, and a facility to create a 'My BP' section." British Pharmacopoeia 2009" eBook - "The complete British Pharmacopoeia 2009" is now available exclusively to "BP 2009" purchasers in an innovative new format. The eBook is greatly suited to this large reference text making the information contained within it available to all of those who wish to access it on the move and away from their desks.British Pharmacopoeia 2009 Concurrent Licence (Online) - "The British Pharmacopoeia" is available as a network licence which can be used on a concurrent user basis. It allows a designated number of staff simultaneous access to the online version of the "British Pharmacopoeia 2009". Once set up, your workforce can then start using the BP at their convenience.

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Stockley's Herbal Medicines Interactions

2009-10-16T02:36:00.001+02:00

Elizabeth Williamson, Samuel Driver, Karen Baxter, "Stockley's Herbal Medicines Interactions"
Pharmaceutical Press 2009 ISBN: 0853697604 400 pages PDF 2,3 MB

This is a professional level major reference work containing information, in A-Z format, on herb-drug, herb-supplement, herb -food and herb-laboratory test interactions; all of which is data referenced. Commercial herbal medicinal products are increasingly consumed on a regular basis by people in the developed world. Often such products are taken concurrently with conventional medicines, frequently without the knowledge of health care professionals. As more evidence has become available, there has been an increasing awareness of the potential and actual problems of interactions, often dangerous, between conventional medicines and herbal medicines. This proposed new major reference brings together available data on approximately 200 of the most commonly used herbal medicines in highly structured, rigorously scientific monographs. Although our texts on herbal medicines and drug interactions include the major well-known interactions, this text is able to treat the subject in considerably more detail.

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FASTtrack: Therapeutics

2009-10-16T02:33:00.001+02:00

Nadia Bukhari, David Kearney, "FASTtrack: Therapeutics"
Pharmaceutical Press 2009 ISBN: 0853697752 200 pages PDF 3,3 MB

This is a revision guide for students providing bullet points of basic information on therapeutics. "FASTtrack" is a new series of indispensable revision guides created especially. The content of each title focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs, case studies, sample essay questions and worked examples. The "FASTtrack" series provides the ultimate lecture notes and is a must-have for all pharmacy undergraduate students wanting to revise and test themselves for forthcoming exams. A "FASTtrack" website includes MCQs, sample online content and much more.

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Pharmacy Student Survival Guide

2009-10-16T02:27:00.002+02:00

The book every pharmacy students must own!
Pharmacy Student Survival Guide is a one-of-a-kind roadmap for excelling in pharmacy practice courses. A combination calculations, kinetics, drug information, medical terminology, and laboratory data book all in one, the Guide helps you organize case information, improve problem-solving skills, learn terminology, and impress faculty during rounds.
Pharmacy Student Survival Guide is presented in three sections that span the entire pharmacy curriculum:
Systems and Expectations covering ethics, communication, monitoring drug therapy, and regulatory agencies, Patient Care Tool Box covering medical terminology, pharmacokinetics, laboratory data, and physical assessment, Topics in Pharmacy Practice covering Drug Information and Drug Literature Evaluation, Community/Ambulatory Care, Institutional Pharmacy Practice, Public Health, Reducing Health Disparities Through Domestic and Global Outreach to the Undeserved, Valuable for both introductory and advanced practice course, Pharmacy Student Survival Guide is a book you will turn to throughout your entire pharmacy education.

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Hospital Pre-registration Pharmacist Training

2009-10-16T02:26:00.000+02:00

Aamer Safdar, Shirley Ip, "Hospital Pre-registration Pharmacist Training"
Pharmaceutical Press 2009 ISBN: 085369785X 256 pages PDF 1,1 MB

This is a practical guide for students; an insight into their hospital preregistration training. It is one of the RPS "Tomorrow's Pharmacist" series. The proposed text aims to provide a practical explanation for undergraduates and preregistration trainees on what to expect from a hospital preregistration training programme. The text uses an informal writing style and is based on tips, hints, past experiences and anecdotes from the authors in their roles as preregistration tutors. The experiences are from a district general hospital and a large teaching hospital perspective.

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2009-10-16T02:15:00.002+02:00

This revised edition assesses the range of non-prescription, over-the-counter medicines that can be recommended for the most frequently encountered minor illnesses. The first edition has been updated to reflect changes in the legal status and availability of products and new opinions on and approaches to treatment. A new section on emergency hormonal contraception is also included. The information is presented in a structured formulary format with products described both generically and by brand name along with supplier details. Each chapter also contains a summary of key points with suggestions regarding the most appropriate products. The book should enable pharmacists, GPs, nurses and other healthcare professionals to make well-informed recommendations and to give patients and customers sound advice on non-prescription medicines.

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Pharmacy Law and Ethics, 9th Edition

2009-10-16T02:13:00.000+02:00

Gordon E. Appelbe, Joy Wingfield, "Dale and Appelbe's Pharmacy Law and Ethics, 9th Edition"
Pharmaceutical Press 2009 ISBN: 0853698279 553 pages PDF 1,9 MB

This is a comprehensive guide to law and ethics for pharmacy practice in the UK. "Dale and Appelbe's Pharmacy Law and Ethics" has become established as the standard student textbook and reference work on this subject in the UK. A knowledge of pharmacy law is a substantial and compulsory component of the undergraduate and pre-registration pharmacy syllabus in the UK and changes to the syllabus and practice require the text to be updated regularly. This revised edition provides a comprehensive guide to the law that affects the practice of pharmacy and the use of medicines in Great Britain, and complete coverage of the pharmacy undergraduate and pre-registration syllabus and British law relating to medicines and poisons.

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LSD By Otto Snow

2009-10-16T02:11:00.001+02:00

Otto Snow, "LSD"
Thoth Press 2003 ISBN: 0966312848 246 pages PDF 11,8 MB

At age 15, Otto developed hemi-paraesthesic migraine headaches. These cluster migraines resemble a stroke. He was given narcotics, barbiturates and ergot alkaloids. The drugs were making him ill. He learned of a new medication that might help. The drug was LSD-25 and it worked.

His physicians would not prescribe LSD so Otto entered the world of LSD. Several laboratories provided him and other patients with the medication. Included are comments and research from the greatest scientists of the twentieth century. Personal satori experiences. At nineteen, Otto discontinued his exploration of LSD.

LSD is the most comprehensive book ever written on the synthesis of LSD. Otto includes the reactions and the chemistry behind the reactions. Many simplified reactions (e.g. diethylamine from vodka, lysergic acid directly from Claviceps sugar culture, coupling agents from scratch). Extractions translated to English.

LSD is written by someone who has been there and knows the subject/chemistry first hand. LSD is as popular today as it was in the 1970s and 1960s. For many it is a party drug, for others it is a medication. The Decade of the Brain heralded in a new interest in psychedelics and their medical application.

The book is illustrated by Tulasne, Chase, Gill and others. LSD is packed with chemistry for future generations of neurochemists and explorers. 275+ references. UV laminated.

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2009-10-16T02:08:00.001+02:00

Pharmacological and Psychosocial Treatments in Schizophrenia: Second Edition By David Castle, David Copolov, Til Wykes, Kim Mueser
Publisher: Informa HealthCare 2008-03-03 262 Pages ISBN: 041542156X PDF 1.8 MB

"A book that aims to give a succinct overview of the holistic treatment of schizophrenia is extremely welcome... I am happy to recommend it to mental health practitioners as a guide to psychosocial treatments" Journal of Mental Health The new edition of 'Pharmacological and Psychosocial Treatments in Schizophrenia' provides an authoritative review of pharmacological and psychosocial treatment interventions for individuals with schizophrenia and related disorders. The text has been fully updated, revised, expanded and new chapters encompass co-morbid general health issues, violence in schizophrenia, the special needs of women with schizophrenia, first-episode psychosis, treatment-resistant schizophrenia, and clinical rating scales in schizophrenia. Each topic is covered with a review of the relevant literature, a summary of the main findings and some tips about how to meet these needs in clinical practice. Thus, the book is both a review and a resource for clinicians and service-providers. The principal Editors and their contributors give an opportunity for leading international experts in the field to contribute and provide an international flavour to the text.

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Gene Therapy of Cochlear Deafness: Present Concepts and Future Aspects

2009-10-16T02:04:00.001+02:00

A. F. Ryan, "Gene Therapy of Cochlear Deafness: Present Concepts and Future Aspects"
S. Karger AG 2009 ISBN: 3805590350 120 pages PDF 6,9 MB

Gene therapy holds great potential for the treatment not only of genetic disorders, but also of many acquired diseases. This is as true for the inner ear as for any other organ. However, the technical challenges that must be overcome before gene therapy becomes more widely used are remarkable. In the inner ear the size, accessibility, delicacy and the involvement of many different cell types present unique conditions.
This volume reviews current concepts and recent research findings of the application of gene therapy to the inner ear. Various forms of gene therapy, disorders that are potential targets for gene therapy, techniques for gene delivery, and mechanisms of gene targeting, and also obstacles that have yet to be overcome are discussed.
This volume will be indispensable reading for otolaryngologists, hearing scientists, audiologists with a special interest in keeping up-to-date on gene therapy for inner ear disorders

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Committee on Clinical Trial Registries - Developing a National Registry of Pharmacologic and Biologic Clinical Trials

2009-10-16T01:53:00.002+02:00

Committee on Clinical Trial Registries - Developing a National Registry of Pharmacologic and Biologic Clinical Trials
Publisher: National Academies Press 2006-06-16 ISBN: 030910078X PDF 124 pages 1.53 MB

Provides workshop report of the Committee on Clinical Trial Registries Board on Health Sciences Policy held June 27, c2005. Topics include the need for clinical trial registries, current registry activities, content of a clinical trial registry, implementation issues, and more. For researchers.

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Principles of Health Care Ethics

2009-10-16T01:48:00.001+02:00

Publisher:Wiley Pages:1118 1994-01-15 ISBN:0471930334 PDF 85 MB

Over 100 authors, representing a wide range of disciplines, nationalities, religions and cultures, write about the many complex ethical dilemmas posed by modern medicine and health care in this richly diverse and thought-provoking collection. The result is a combination of reference work and narrative, both useful and accessible as a professional resource, and informative and readable as an overview of current thinking. The books use, analysis and critique of four moral principles—respect for autonomy, beneficence, non-maleficence, and justice—provide a linking theme throughout, giving the reader an appreciation of the power of these basic principles in providing an analytical framework for moral reflection on ethical issues in health care. The topics discussed in this book are relevant to everyone working in, or associated with, medicine and health care, whether student, practitioner, teacher or researcher, but its appeal will also extend to those in the fields of philosophy, medical law, sociology and theology, and the general reader concerned about the many moral problems that arise in medical practice.

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Wilson & Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry 11th Ed.

2009-10-16T01:43:00.002+02:00

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Understanding Drugs and Behaviour

2009-10-16T01:41:00.000+02:00

Understanding Drugs and Behaviour
Wiley July 23, 2004 ISBN: 0471986402 332 pages PDF 6 MB

This textbook provides an introduction to the action that various drugs have on the brain and behaviour. Because most students find this topic interesting, it creates an opportunity for learning about basic physiology that can otherwise be perceived as tedious. But this is not just a physiology text in a different guise, since social consequences and health implications are covered too, making it ideal for use in health psychology and health promotion also.

Chapters include common substances such as tobacco and alcohol, "hard" drugs such as amphetamines, Ecstasy and cocaine, with a final section considering drugs used in the treatment of major psychiatric disorders. Written by experienced lecturers, this book aims to make teaching easy by including chapter overviews, questions that the student should be able to answer at the end of each chapter, and a clear structure throughout.

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USP NF 2009 (United States Pharmacopeia 32 / National Formulary 27)

2009-10-16T01:31:00.005+02:00

The United States Pharmacopeia–National Formulary and its Supplements become official six months after being released to the public. The USP–NF, which is released on November 1 of each year, becomes official on May 1 of the following year.
This change was adopted to give users more time to bring their methods and procedures into compliance with new and revised USP–NF requirements.
The table below describes the new official dates. The 2008 USP31–NF26, and the Supplements and Interim Revision Announcements (IRAs) to that edition, will be official until May 1, 2009, at which time the USP32–NF27 becomes official

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Case files - Physiology

2009-10-16T01:25:00.000+02:00

Eugene Toy, Norman Weisbrodt, William Dubinsky, Roger O'Neil, Edgar Walters, Konrad Harms, "Case Files Physiology, Second Edition"
MgH 2008 ISBN: 0071493743 456 pages PDF 4,2 MB

REAL LIFE CLINICAL CASES FOR THE COURSE EXAMS AND USMLE STEP 1

"This extremely useful book reinforces the relationship between basic science and clinical medicine for students. It will help them either review or learn basic physiology as it applies to medicine, which should strengthen their diagnostic and therapeutic skills. 3 Stars."--Doody's Review Service

You need exposure to clinical cases to pass course exams and ace the USMLE Step 1. Case Files: Physiology presents 50 real-life clinical cases illustrating essential concepts in microbiology. Each case includes and easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, physiology pearls, and USMLE-style review questions. This interactive system helps you learn instead of memorize.

50 clinical cases, each with USMLE-style questions
Clinical pearls highlighting key physiology concepts
Primer on how to approach clinical problems and think like a doctor
Proven learning system based on award-winning research boosts your shelf exam score

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Nutrition and oral Medicine

2009-10-16T01:21:00.002+02:00

Riva Touger-Decker, David A. Sirois, Connie C. Mobley, "Nutrition and Oral Medicine"
Humana Press 2004 ISBN: 1588291928 416 pages PDF 5 MB

Benchmark studies by internationally recognized leaders in dentistry and nutrition review the many links connecting nutrition and dietary practices to oral diseases and disorders. The authors examine the effects of diet and its nutrient components on the development, growth, maintenance, prevention, and treatment of diseases in the oral cavity. Topics range from the relation between oral and general health, nutrition/diet and systemic health, and nutrition/diet and oral health, to select oral and systemic diseases with known nutrition and oral health interfaces; also cutting-edge research issues regarding the relationship of individual anioxidants, trace elements, polyphenols, and other nutrient substrates.

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New Drug Discovery and Development

2009-10-15T19:02:00.000+02:00

Daniel Lednicer, «New Drug Discovery and Development»
Wiley ISBN: 0470007508 2006 PDF 190 pages 2.78 MB

A case history approach to drug synthesis and discovery
Discover the origins of some of the most popular drug therapies on the market today, including penicillin, Minoxidil, Viagra, and "the pill." This guide to drug synthesis and discovery focuses on case histories. Organized by drug category, the guide introduces readers to the rich interplay of research and serendipity that is responsible for many commonly prescribed drugs today. Moreover, the author demonstrates how the discovery and development of a new drug or drug category creates a domino effect, leading to the development of newer therapeutics as pharmaceutical companies compete to satisfy market demands.

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Drug Discovery and Development for Alzheimer's Disease (2000)

2009-10-15T19:00:00.000+02:00

Howard M. Fillit MD, Alan W. O'Connell PhD, "Drug Discovery and Development for Alzheimer's Disease (2000)"Springer Publishing Company; 1 edition (December 15, 2001) English 082611542X 280 pages PDF 14.26 MB(Institute for the Study of Aging) First volume in a new annual series presents the latest findings of an international group of academic and biotechnological researchers. Topics range from early detection programs focusing on genetic factors to the use of telephonic screening and MRIs.
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Stedman's Medical Dictionary 28th Edition

2009-10-15T18:55:00.001+02:00

Stedman's Medical Dictionary 28th Edition
2162 pages English 2006 ISBN-10: 0781764505 109.9Mb Publisher: Lippincott Williams & Wilkins

Stedman’s Medical Dictionary, 28th Edition, is the most reliable, must-have resource available for healthcare professionals. The 28th Edition contains more than 107,000 total terms, with more than 5,000 new to this edition. Furthermore, this edition has been thoroughly reviewed and updated by consultants from all the major medical and health science specialities including Endocrinology, Gastroenterology, Geriatrics, and Rheumatology.

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Targeted Cancer Immune Therapy (2009)

2009-10-15T18:53:00.000+02:00

Targeted Cancer Immune Therapy
Publisher: Springer Language: English ISBN:1441901698 343 pages Data: 2009 PDF 3 Mb

Description: The principle of cancer immune therapy remains the stimulation of the immune system to control and destroy tumors, but the scope is expanded in steady and fast pace, the approach is modernized every few years, new molecules are revealed annually, and the understanding of the mechanisms is getting deeper and deeper.

Targeted Cancer Immune Therapy covers cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were selectively described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were heavily discussed in regard to the anti-tumor function and application in treating tumors. In the second section, Cell-based Immune Therapy, the focus was given to engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. The cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen presenting cells, antigen specific effector cells, and the tumor microenvironment. In the third section, Targeted Immune Therapy, the focus was given on rearticulating the antibody therapy for boosting immune response, which includes immunocytokines, "T-body", and tumor targeted CpG ODN. Immunocytokines represent a new class of biopharmaceuticals composed of two well known immune components – antibodies and cytokines – with the unique ability to target cytokines to the tumor microenvironment and thereby activate antitumor responses. Some or all of these innovative approaches may ultimately become the future effective immune therapy for treating malignancy.

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The complement system-Novel Roles in Health and Disease

2009-10-15T18:44:00.002+02:00

Janos Szebeni, "The Complement System: Novel Roles in Health and Disease"
Kluwer Academic Publishers / Springer; 1 edition (June 10, 2004) English 1402080557 565 pages PDF 10.59 MB

The Complement System: Novel Roles in Health and Disease surveys the advances in basic and applied research on the complement system over the past few years. Complement is a major protein network in blood that has been traditionally conceived as part of the immune system, a proinflammatory cascade engaged in nonspecific antimicrobial defence. However, it became clear recently that this system also plays an essential role in specific, adaptive immune responses, as well as in many basic physiological processes including cardiovascular regulation, pregnancy and tissue regeneration, just to mention a few. Complement proteins are widely involved in the immune evasion tactics of infectious microbes and cancer cells, and derangement of complement function contributes to numerous autoimmune, allergic and acute catastrophic diseases. Because pharmacological manipulation of the complement system provides therapeutic benefit in many of these conditions, we may be very close to widespread clinical use of a new class of drugs influencing complement activation or action. In fact, complementology may be one of the most versatile and dynamic subdisciplines in medicine today. The 25 reviews of this volume, written by prominent experts, provide state-of-art insights into the various aspects of an amazing progress in this field.

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Book of World Congress of Dermatology

2009-10-15T18:34:00.000+02:00

C. C. Zouboulis, Maria Isabel Herane, D. Thiboutot, "Acne: Symposium at the World Congress of Dermatology, Paris, July 2002"
S. Karger Medical and Scientific Publishers; 1 edition (January 2003) English 3805575483 74 pages PDF 1.48 MB

The proceedings of the Symposium on Acne which took place during the 20th World Congress of Dermatology in July 2002 in Paris review the current and future aspects of research, clinical entities and treatment of acne. In the foreword by Prof. John S. Strauss (Iowa City) the most important data are summarized. The papers presented are the results of a cooperation of international experts introducing innovative data on epidemiology, comedogenesis and inflammation, acne in infancy, acne genetics, topical and systemic treatment, bacterial resistance, hormonal therapy, and less common methods of acne therapy. This publication equally addresses clinicians and scientists interested in the current and future trends of the treatment of acne as well as the auspicious development acne research will experience.

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Drug targeting ( Organ-Specific Strategies )

2009-10-15T18:32:00.001+02:00

Grietje Molema, Dirk K. F. Meijer, Raimund Mannhold, Hugo Kubinyi, Hendrik Timmerman, "Drug Targeting Organ-Specific Strategies"
Wiley-VCH; illustrated edition (January 15, 2001) English 3527299890 381 pages PDF 2.97 MB

How are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is "Drug Targeting".
This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.

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We are back

2009-10-15T18:08:00.003+02:00

Back with new books
with new encyclopedias
new programs
and new Sections of the site and our career
for pharmacy...Only pharmacy
we will try to get into more action
more exclusives
just to gain more and more of our career
Sorry for that long time apart
we promise that the coming period will be very Filled with surprises
wait for us
and let us Begin

.

2009-02-06T20:42:00.004+02:00

.

Dear all

For reasons beyond our control , we will have to stop to add new books for a short time .. Sorry .. wait for us .. the whole site will still be .. but just new posts which will be stopped .So, try to browse the rest of our library, which contains about 900 books in Pharmacy classified accurately in order to serve all your needs in this science , and can fully satisfy your requests.
We promise that we will come back to add new books very soon .. two weeks or a little more.

.

Polymer Therapeutics 1, 2 Polymers as Drugs, Conjugates and Gene Delivery Systems

2009-01-27T09:26:00.001+02:00

Polymer Therapeutics I Polymers as Drugs, Conjugates and Gene Delivery Systems (Advances in Polymer Science, Vol. 192)

Polymer Therapeutics I Polymers as Drugs, Conjugates and Gene Delivery Systems (Advances in Polymer Science, Vol. 192)
Publisher: Springer ISBN: 3540292104 2006 Pages: 213 PDF 4.8 MB

Table of contents
1 Duncan, H. Ringsdorf, R. Satchi-Fainaro: Polymer Therapeutics: Polymers as Drugs, Drug and Protein Conjugates and Gene Delivery Systems: Past, Present and Future Opportunities.-
2 P.K. Dhal, S.R. Holmes-Farley, C.C. Huval, T.H. Jozefiak: Polymers as Drugs.-
3 R.J. Amir, D. Shabat: Domino Dendrimers.-
4 G. Pasut, F.M. Veronese: PEGylation of Proteins as Tailored Chemistry for Optimized Bioconjugates.- E. Wagner, J. Kloeckner: Gene Delivery Using Polymer Therapeutics.-

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Polymer Therapeutics II Polymers as Drugs, Conjugates and Gene Delivery Sytems (Advances in Polymer Science, Vol. 193)

Polymer Therapeutics II Polymers as Drugs, Conjugates and Gene Delivery Sytems (Advances in Polymer Science, Vol. 193)
Publisher: Springer ISBN: 3540292111 2006 Pages: 200 PDF 3.9 MB

Table of contents
1 R. Satchi-Fainaro, R. Duncan, C.M. Barnes: Polymer Therapeutics for Cancer: Current Status and Future Challenges.-
2 N. Nishiyama, K. Kataoka: Nanostructured Devices Based on Block Copolymer Assemblies for Drug Delivery: Designing Structures for Enhanced Drug Function.-
3 H. Maeda, K. Greish, J. Fang: The EPR Effect and Polymeric Drugs: A Paradigm Shift for Cancer Chemotherapy in the 21st Century.-
4 J.S. Ellis, S. Allen, Y.T. A. Chim, C.J. Roberts, S.J.B. Tendler, M.C. Davies: Molecular-Scale Studies on Biopolymers Using Atomic Force Microscopy.-
5 A.V. Kabanov, E.V. Batrakova, S. Sherman, V.Y. Alakhov: Polymer Genomics.-

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Pharmaceutical Perspectives of Nucleic Acid-Based Therapy

2009-01-27T09:19:00.000+02:00

Ram I. Mahato, Sung Wan Kim "Pharmaceutical Perspectives of Nucleic Acid-Based Therapy"
CRC 2002-06-27 ISBN: 041528385X 568 pages PDF 7,3 MB

Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications, with an emphasis on cancer and cardiovascular and autoimmune diseases. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by controlling gene regulation, transcription, translation and replication.

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Analytical Profiles of Drug Substances and Excipients , vol 28

2009-01-27T09:18:00.001+02:00

Analytical Profiles of Drug Substances and Excipients
Academic Press ISBN: 0122608267 1999-10-05 PDF 508 pages 12 Mb

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.

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Encyclopedia of Substance Abuse Prevention, Treatment, and Recovery

2009-01-27T09:15:00.001+02:00

Gary L. Fisher, Nancy A. Roget, "Encyclopedia of Substance Abuse Prevention, Treatment, and Recovery"
Sage Publications, Inc 2008-11-11 ISBN: 1412950848 1152 pages PDF 11,4 MB

Reflecting the recent explosion in the knowledge base of all aspects of the alcohol and drug abuse field, the Encyclopedia of Substance Abuse Prevention, Treatment, and Recovery presents state-of-the-art research and evidence-based applications. The Encyclopedia’s approximately 350 A-to-Z signed entries focus on the information that addiction treatment and prevention professionals and allied health professionals need to effectively work with clients.
Features
Provides comprehensive and authoritative coverage of such areas as the neurobiology of addiction, models of addiction, sociocultural perspectives on drug use, family and community factors, prevention theories and techniques, professional issues, the criminal justice system and substance abuse, assessment and diagnosis, and more
Focuses on concepts of addiction and treatment practices, but also addresses commonly used and abused drugs, including recreational, prescription, and over-the-counter
Offers a Reader's Guide that lists topic categories with specific entries
Presents cross-references at the end of each entry to help readers locate related information in other entries, as well as Further Readings for those who wish to pursue topics in more depth
Includes an appendix listing of58 different drugs and substances with corresponding relevant entries
The Encyclopedia of Substance Abuse Prevention, Treatment, and Recovery is intended for use by pre-service and in-service addiction prevention and treatment providers and allied professionals in the fields of criminal justice, counseling, social work, public health, nursing, medicine, other health care professions, education, and family studies.

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Antimicrobial Chemotherapy

2009-01-27T09:14:00.000+02:00

David Greenwood, Roger Finch, Peter Davey, Mark Wilcox, "Antimicrobial Chemotherapy"
Oxford University Press, USA 2007-02-12 ISBN: 0198570163 504 pages CHM 4,7 MB

Instilling good prescribing habits in young doctors is essential for the benefit of patients and to preserve the value of the antibiotic revolution that altered medical practice in the second half of the twentieth century. These concerns underlie the approach taken in the new edition of this successful book. The text provides a comprehensive and up-to-date account of the principles of antimicrobial chemotherapy as an aid to informed, rational prescribing. Care is taken to address all aspects of antimicrobial drug use, including those specific to developed and developing countries of the world. The authors are international experts with a long standing interest in the role of education as a means of promoting an understanding of the benefits and limitations of antimicrobial chemotherapy in physicians, surgeons and other health care workers. The book offers a structured approach to the subject in four themed sections, each of several chapters. A historical introduction is followed by a section outlining the basic properties of antibacterial, antifungal, antiparasitic and antiviral (including antiretroviral) drugs. The next section explains the various facets of antimicrobial drug resistance - which threatens to undermine the continued efficacy of antimicrobial agents - and effective ways of countering the threat. Therapeutic use is covered in two sections: one introduces readers to the general principles that inform the rational prescribing of antimicrobial drugs; the second deals with practicalities of the use of antimicrobial agents in specific clinical conditions. The book ends with a description of the ways in which drugs are developed and marketed. There are extensive recommendations for further reading.

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Anti-IgE Therapy in Asthma and Allergy

2009-01-27T09:12:00.000+02:00

S.H. Arshad, K. Suresh Babu, Stephen Holgate "Anti-IgE Therapy in Asthma and Allergy"
Informa HealthCare 2001-01-15 ISBN: 1841840904 64 pages PDF 1 MB

Little new has been introduced into the armamentarium for asthma therapy in the last thirty years apart from improvements in b2-adrenoceptor agonists, corticosteroids and cysteinyl leukotriene antagonists. However, the introduction of a fully humanised monoclonal antibody to immunoglobulin E (IgE) (omalizumab), should provide a new way of treating allergic disorders, with effects that extend beyond a single affected organ and tissue. The precise role of this new agent in treatment guidelines will need to be carefully evaluated, but its clear efficacy and safety provide a strong statement about the importance of IgE across the full spectrum of allergic disease. This pocketbook provides an illustrative summary of the role of IgE in the pathogenesis of asthma and allied allergic disorders, as well as the effects of anti-IgE therapy in the management of these conditions.

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Infectious Disease: A Clinical Short Course (In Thirty Days Series)

2009-01-27T09:10:00.001+02:00

Frederick S. Southwick "Infectious Disease: A Clinical Short Course (In Thirty Days Series)"
McGraw-Hill Professional 2007-12-10 ISBN: 0071477225 460 pages PDF 4,3 MB

No other resource makes clinical infectious diseases more manageable and easy to master than Infectious Diseases: A Clinical Short Course. This one-of-a-kind self-instruction tool is organized by system/region as opposed to pathogens-simulating how common pathogens and disorders would be encountered in rounds or in practice. For this reason, this remarkable resource is unsurpassed for learning to associate pathogens with their corresponding impact on actual patients.
Features:
• A true, concise “short course” format that can be read and understood in the time of a 30-day infectious disease rotation
• Numerous case examples-appropriate for PBL and integrated curricula-to further highlight clinical application of the content
• Key points summaries and Guiding Questions that drive home core concepts and aid comprehension
• 24 eye-catching color plates that depict major pathogens and reinforce the impact of clinical infection
• NEW! An even more concise and streamlined format designed to help you learn the most in the least amount of time

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Cancer Drug Design and Discovery

2009-01-27T09:08:00.000+02:00

Stephen Neidle "Cancer Drug Design and Discovery"
Academic Press 2007-10-15 ISBN: 0123694485 448 pages PDF 7 MB

The ultimate source of information on the design of new anticancer agents, emphasising small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumours. Unique sections explain the basic underlying principles of cancer drug development and provide a practical introduction to modern methods of drug design. Appealing to a broad audience, this is an excellent reference for translational researchers interested in cancer biology and medicine as well as students in pharmacy, pharmacology, or medicinal and biological chemistry, and clinicians taking oncology options.

* Covers both currently available drugs as well as those under development
* Provides a clinical perspective on trials of new anticancer agents
* Presents drug discovery examples through the use of case histories

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Peptide-Based Drug Design: Methods and Protocols

2009-01-27T09:04:00.002+02:00

Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology™ series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research.

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Pharmaceutical Design And Development: A Molecular Biology Approach

2009-01-27T08:59:00.001+02:00

This volume aims to introduce researchers in pharmaceutical and allied industries to the concepts and latest developments in the application of biotechnology recombinant DNA and monoclonal antibodies to drug development. The author puts biotechnology in perspective, introducing the basic concepts of cell and molecular biology and discussing both the application of protein drugs and the design of new molecular entities. The study examines the use of proteins and assay systems produced via biotechnology to the development of small-molecule drugs. A discussion of gene and somatic cell therapies is included, along with developments in diagnostic methods resulting from biotechnology. The text concludes by examining future prospects and likely developments in the field.

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Microencapsulation

2009-01-27T08:55:00.002+02:00

Presenting practical approaches to complex formulation problems, this outstanding reference provides a thorough overview of particulate delivery systems-emphasizing specific preparation, characterization, and evaluation methods, as well as potential applications in areas such as pharmacy, medicine, cosmetology, and agriculture.

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Local Drug Delivery for Coronary Artery Disease: Established and Emerging Applications

2009-01-27T08:50:00.000+02:00

Edoardo Camenzind, Ivan De Scheerder "Local Drug Delivery for Coronary Artery Disease: Established and Emerging Applications"
Inf HealthCare 2005-06-14 ISBN: 1841840459 608 pages PDF 9 MB

Restenosis remains the Achilles heel of Percutaneous Coronary Interventions. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response, and drug eluting stents-using the stent as a platform for local drug delivery-are now considered a significant breakthrough in interventional cardiology. Pioneers in the field, the editors of Local Drug Delivery for Coronary Artery Disease have assembled an excellent team of contributors who offer their experience with threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. They share their expertise on all aspects of the field, including a discussion of results from preclinical and clinical studies, and they examine alternative methods of molecular delivery to the vessel wall. With coverage of the most current methods and applications, as well as a host of photographs illustrating their implementation, this book will serve as an excellent reference for cardiologists, pharmacologists, cardiac surgeons, and trainees.

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Oral Lipid-Based Formulations: Enhancing the Bioavailability of Poorly Water-Soluble Drugs

2009-01-27T08:43:00.000+02:00

Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem of major significance, the pharmaceutical industry has been slow to apply and further develop this technology. This title provides a comprehensive summary of the theoretical and practical aspects of oral lipid-based formulations for use in industry, and provides further insights into a developing technology expected to assume increasing prominence in years to come.

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P & G Pharmacy Handbook, Second Edition

2009-01-27T08:37:00.001+02:00

It is crucial that pharmacists understand the language of health care professionals and, in turn, can convey the information in an understandable fashion to patients. Procter & Gamble Pharmacist's Handbook, Second Edition facilitates this communication. Now, all in one place, you can have medical terms, abbreviations, and patient counseling principles right at your fingertips. The handbook begins with an Inverted Medical Dictionary to translate lay terminology to more technical vocabulary and an Eponyms section to translate medical terminology to language that is comprehensible to patients. The Dictionary shows how to analyze the medical terms by identifying its root, suffix, and prefix. This examination is supplemented with numerous tables of common roots, suffixes, and prefixes. The book concludes with a glossary of managed care terms that will help you understand the language of the insurance community. Another critical responsibility of a pharmacist is to clearly comprehend a prescription. The sections containing Medical Abbreviations and Terms Used in Prescription Writing will aid in this vital task. Also included in the handbook are general references, such as normal laboratory values, conversion factors, and weights and measures. These features make Procter & Gamble Pharmacist's Handbook, Second Edition a convenient and handy resource for the practicing pharmacist.

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ChemSketch 4.0

2009-01-27T08:33:00.002+02:00

EASY , SMALL

The global smash hit, all-purpose chemical drawing and graphics software. Use templates or free-hand. Click and draw molecules, ions, stereobonds, text, polygons, arrows, etc. Automatic calculation of MW, and formula. See estimates of density, refractive index, molar volume, etc. It has the new tools for drawing radicals and ion-radicals quickly and easily, supports a Long File Names, as well as presents the ability to access the I-Lab site through so that you have instant on-line access to ACD/Labs prediction modules.

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The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals

2009-01-20T14:42:00.007+02:00

The Merck Index is a one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs. Each monograph in this authoritative reference source is a concise description of a single substance or a small group of closely related compounds.

Compounds included:

1- human and veterinary drugs

2- biotech drugs and monoclonal antibodie

3- substances used for medical imaging

4- biologicals and natural products

5- plants and traditional medicines

6- nutraceuticals and cosmeceuticals

7- agriculturals, pesticides and herbicides

8- Organic chemicals used in research

9- Food additives and supplements

10- dyes, colors and indicators

11- environmentally significant substances

Information provided:

1- chemical, common and generic names

2- Over 15,000 trademarks and associated companies

3- CAS Registry Numbers for over 12,000 compounds

4- Over 8,500 chemical structures

5- molecular formulae, weights and percentage composition

6- capsule statements identifying compound classes and scientific significance

7- scientific and patent literature references

8- physical and toxicity data

9- therapeutic and commercial uses

10- caution and hazard information

In addition, there are more than 700 new and completely revised monographs, thousands of new references, trademarks and uses added to existing monographs. Now includes a companion CD-ROM which features 989 monographs no longer available in print, organic name reactions, supplemental tables and a new user interface for user-friendly searching.

Features of the CD:

Searchable by keywords, references, and numerical properties
Search the complete contents of the 14th edition, plus nearly a thousand monographs archived from previous editions
Comes with a free one-year subscription to the Merck Index Internet Edition
Windows-compatible CD powered by CambridgeSoft's ChemFinder
Extensively revised supplemental tables now including acronyms, vaccines, and physical constants
More than 70 pages of hard to find information in one easy-to-use place

FREE Download Links: 5 PARTS
Part-1

Part-2

Part-3

Part-4

Part-5

Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition

2009-01-20T14:31:00.004+02:00

Product Details

Hardcover: 848 pages
Publisher: CRC; 2 edition (July 25, 2007)
ISBN-10: 0849387965
ISBN-13: 978-0849387968
Editorial Reviews
Product Description
Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generation drugs, the book evaluates the technology as a whole and offers new directions and avenues of research and development.

Divided into five parts, the book begins with a thorough introduction to the mechanism of antisense drug action including the RNase H mechanism, small RNA silencing pathways, and the potential therapeutics of splice switching oligonucleotides. Leading researchers demonstrate the basics of oligonucleotide therapeutics in part two by delineating medicinal chemistry, pharmacokinetics, and delivery routes such as liposomal formulations for nucleic acid delivery. Part three details hybridization based drugs and considers the dramatic advances represented by 2 methoxyethyl chimeric antisense inhibitors and duplex RNA drugs. Other chemical classes of drugs and mechanisms of action are described in part four with further discussions on improving the second generation antisense drugs. The final part delves deeply into therapeutic applications. Contributing authors examine the potential of antisense drugs for the alleviation of cardiovascular diseases, metabolic diseases, inflammatory diseases, cancer, neurological disorders, and immune modulation.
Presenting a highly detailed, lucid discussion of the remarkable advances in the field, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition provides the platform for researchers to continue to aggressively pursue the great opportunity represented by this exciting technology.

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Atlas of Microscopy of Medicinal Plants, Culinary Herbs and Spices/Betty P. Jackson

2009-01-20T14:06:00.001+02:00

As this book is intended primarily for use in the verification of materials, for ease of location we have arranged the ,alphabetical order according to their commonly accepted names. We have also provided separate indices of Synonyms and Botanical Sources. “All the drawings in this book have been made solely by ourselves from previously authenticated samples. For the drugs and spices, which usually occur commercially in the powdered form, number 60 grade powders were prepared for examination, but for the culinary herbs, which are more usually available in the whole or broken condition, fragments of a suitable size were examined. The drawings were made at a magnification of 500, using a camera lucida, from fresh mounts prepared as described in the section on Practical Methods. In preparing the drawings our aim has been to illustrate the diagnostic characters for each material and we have excluded cell *******s which are common to a morphological group but are not otherwise diagnostic, for example, aleurone grains and fixed oil globules in seeds. The descriptions, similarly, are intended to give a detailed account of the actual characters seen in the fragments rather than the full histology of the plant organ from which the materials are derived. We have quoted dimensions of cells and other particles only when they are of value in distinguishing between closely similar materials.” Although chemical methods of analysis, especially chromatography, are now accepted as standard techniques for the identification of many vegetable materials, microscopical structure is long established as providing a most useful and reliable criterion. Microscopy is particularly applicable to the exmaination of mixtures when individual components can readily be recognised whereas no satisfactory chromatographic identification would be possible. Microscopy also has the advantages of requiring only small quantities of the material and, once the technique has been acquired, a conclusion as to whether or not a sample is genuine can be reached very rapidly.

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The Pharmacology of Chinese Herbs, Second Edition

2009-01-20T14:03:00.000+02:00

Publisher: CRC
Number Of Pages: 544
Publication Date: 1998-07-27
ISBN-10 / ASIN: 0849316650
ISBN-13 / EAN: 9780849316654
Binding: Hardcover

Book Description:

Records cataloging the healing powers of natural substances - plants, minerals, and animal byproducts - date back more than 4,000 years. There is no denying the effectiveness of traditional Chinese medicine, yet - until recently - the roots of this knowledge were largely lost in superstition and folklore. However, the use of herbs as an alternative medical treatment for many illnesses has increased steadily over the last decade, particularly since such herbs are categorized as "Natural Food Products" and are not yet subject to strict control by the FDA.Reports published in 1996 indicate that more than 10% of the US population has used herbal remedies.This book does not debate the value of Eastern or Western medicine but brings together Chinese herbal lore and Western scientific methods in a current, comprehensive treatise on the pharmacology of Chinese herbs. This second edition of The Pharmacology of Chinese Herbs presents the chemical composition, pharmacological action, toxicity, and therapeutic value of 473 herbs. The book: · Classifies herbs according to their therapeutic value · Informs how active ingredients in herbs may adversely interact with other herbs or drugs · Evaluates which herbs have the potential for more investigation and possible use as drugs · Describes the pharmacological action of each herb based on recent scientific study and describes each herb according to Chinese pharmacopoeia and folk medicine · Provides a review of Chinese medical history · Presents information on how to use modern chemical techniques for enhancing or modifying herbal ingredients into better agents with more strength and activity What's New in the Second Edition Discussions on: · Herbs and their specific effects on the immune system · Herbs and fertility/infertility · Anti-cancer herbs · Anti-HIV herbs · Anti-malarial herbs · Ginseng and ginsenosides · Anti-Alzheimer herbs · Herbs affecting the nervous system

Summary: Not worth the money, Nothing you cannot find on pubmed.com
Rating: 2

I'm shipping this book back. It isn't worth the price tag given the info it provides. It is basically a regurjitation of pubmed.com research and abstracts. In fact with some of the entries I can almost read verbatim the abstract that it references. (In general I find CRC press books too pricey)

Summary: Concise guide to the scientific base of major herbal drugs

Rating: 5

Very outstanding among the books on chinese herbs written in English (to be fair, many better books in Chinese exist but not well translated!)

Starting from the chemistry and ending with the toxicology, each important herbs included are presented in a well-balanced format; the therapeutic values are thus projected clearly on the empirical grounds.
The new edition is an updated gist of those related scientific works done but could not be tracked on the great MedLine due to the ******** barrier.

Summary: Thorough...a bit pricy, but well worth the expense.
Rating: 5

As a Ph.D. student in biochemistry I have sought out critical references that would be accurate and legitimate treatises on the biochemistry and pharmacology of herbs. If one is truly interested in understanding the biochemistry and pharmacology of Chinese herbs, then this is the reference to purchase. Very intelligently presented in a concise scientific journal format, presenting critical and relevant studies on the herbs as they are currently understood with many references to the original research papers. I would certainly purchase other titles similar to this if their coverage of other herbs (e.g. South American, Ayurvedic) were as comprehensive, relevant, and credible as this one. Not for the herbologist interested in a hokey metaphysical distortion of truth. Ideal for the intelligent and/or educated layman that really wants to know what compounds are present in various Chinese herbs and what their activities are.
Pitfalls: Some listings are very brief (less than a page) For instance the discussion of Centella asiatica is only 1/2 page and listed under antipyretic herbs and makes no mention of nootropic effects if they, in fact, exist-Nobody's perfect.

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Pharmacy Ethics and Decision Making

2009-01-20T14:00:00.000+02:00

Pharmacy Ethics and Decision Making
By Joy Wingfield, David Badcott

Publisher: Pharmaceutical Press

Number Of Pages: 313
Publication Date: 2007-08-13
ISBN-10 / ASIN: 0853696896
ISBN-13 / EAN: 9780853696896

A primer in professional ethics and accountability for practising pharmacists. It provides a complementary resource to the RPSGB Code of Ethics, to guide pharmacists in their professional practice.

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The Pharmacopoeia of the United States of America: Facsimile of the First Edition (1820)

2009-01-20T13:56:00.000+02:00

The Pharmacopoeia of the United States of America: (The United States Pharmacopoeia). By General Medical Convention, United States Pharmacopeial Convention Committee of Revision, United States Pharmacopœial Convention, General Convention for the Formation of the American Pharmacopoeia, National Convention for Revising the Pharmacopoeia Published by United States Pharmacopoeial Convention, Inc., 1820-1975., 1820

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Colloidal Biomolecules, Biomaterials, and Biomedical Applications

2009-01-20T13:54:00.000+02:00

By

Publisher: Marcel Dekker
Number Of Pages: 496
Publication Date: 2003-08-01
Sales Rank: 2815297
ISBN / ASIN: 0824747798
EAN: 9780824747794
Binding: Hardcover
Manufacturer: Marcel Dekker
Studio: Marcel Dekker
Average Rating:
Total Reviews:
Book News Annotation:
Fifteen chapters by researchers from around the world detail an original homogenous assay for biomolecule detection and capture through duplex colloid particles, as well as new methods for using peptides in particle aggulation. The book presents the utilization of colloids in diagnosis and therapy, with recent research results, new methodologies, and several applications. Studies reporting on the interactions (adsorption, desorption, covalent coupling, etc.) between biomolecules (nucelic acids, proteins, antibodies, peptides, viruses, etc.) are also included.

Book Description:

Colloidal Biomolecules, Biomaterials, and Biomedical Applications is an authoritative presentation of established and recent techniques promising to revolutionize the areas of biomedical diagnostics, therapeutics, pharmaceutics, and drug delivery. This exceptional book details an original homogeneous assay for biomolecule detection and capture through duplex colloid particles, as well as new methods for utilizing peptides in particle agglutination. Featuring contributions from over 30 prominent researchers, it investigates physical studies of the agglutination of sensitive latexes, and indicates benefits to drug delivery through supercritical fluid process production of polymer particles.

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European Pharmacopoeia, 4th edition

2009-01-15T00:16:00.003+02:00

The European Pharmacopoeia is a single reference work for the quality control of medicines in Europe. Several legal texts make the European Pharmacopoeia mandatory:A Convention on the Elaboration of a European Pharmacopoeia ratified in 2003 by 31 European countries and the European Union; European Union directives 2001/83/EC and 2001/82/EC,on medicines for human use and for veterinary use, respectively, maintain the mandatory character of European Pharmacopoeia specifications on medicines as regards their qualitative and quantitative composition and the tests to be carried out on these medicines, the raw materials used in production and the intermediates of synthesis. All producers of medicines or substances for pharmaceutical use therefore must apply the quality standards of the European Pharmacopoeia for the marketing and use of these products in Europe. The texts of the European Pharmacopoeia are legally binding and compliance is enforced by the administrative or juridical authorities. The national authorities of the member states are bound to apply them if necessary replacing any national monograph on the same subject.

The 4th Edition consists of an initial volume 2002 (4.0) and a collection of 8 non-cumulative supplements (4.1) published three times a year following the decisions of each session of the European Pharmacopoeia Commission. With supplement 4.6, the 4th Edition comprises 1750 specific monographs, 285 general methods illustrated by figures or chromatograms and 2140 reagents. Every 4 months a new volume enters into force.

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Neonatal Formulary: THE 5th edition ,Drug Use in Pregnancy and the First Year of Life

2009-01-15T00:12:00.003+02:00

The Neonatal Formulary is a unique book providing advice on the safe use of drugs during pregnancy, labour and throughout the first year of life. Thoroughly updated, this fifth edition draws on the experience of an increasingly international group of neonatologists and is now a well established reference on prescribing in infancy. It covers all the drugs commonly used in the perinatal period, including those used for fetal treatment, and summarizes how the prescribing of each has to adapt to changes in drug elimination during the first year of life.

Key features for the fifth edition include:

fully updated monographs and references
20 full monographs for diseases more commonly seen in the tropics
invaluable information on dose sizes and administration for babies
further inclusion of evidence from relevant RCTs and systematic reviews from the Cochrane database
a free access website with regular updates and links to other useful information.

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Pharmaceutical Manufacturing Encyclopedia, 3rd Edition

2009-01-15T00:09:00.001+02:00

This industry standard encyclopedia on pharmaceutical manufacturing processes has been completely updated in this 3rd Edition with FDA approved drugs up to the summer of 2004. This four volume set gives details for the manufacture of 2,226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:

Theraputic Function
Chemical and Common Name
Structural Formula
Chemical Abstracts Number
Trade Name, Manufacturer, Country, and Year Introduced
Raw Materials
Manufacturing Process

In addition, references are also cited to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products.

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Get Well at Home: Complete Home Health Care for the Family

2009-01-15T00:07:00.000+02:00

Get Well at Home: Complete Home Health Care for the Family
Richard A. Hansen Shiloh Medical Publications Pages:464 1995-01 ISBN:0964391414

Get Well at Home is one of the most useful and practical books to have at home. It's wonderful to have a book that gives natural remedies, first aid, and practical information by a qualified doctor. It's worth every penny!

Get Well At Home has been written, not only for laymen, but also for those special physicians and nurses who are seeking rational and natural approaches to common diseases. Together with detailed and systematic study of the medical literature, this introduction to simple remedies contains knowledge with which every medical practitioner should be familiar. This author anticipates that Get Well At Home will become one of the most valued health references in every family library. It is to the health and happiness of you, dear reader or patient, that time has been devoted in translating a unique medical education into terms understandable by everyone.

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Using Mass Spectrometry for Drug Metabolism Studies

2009-01-14T23:55:00.000+02:00

Using Mass Spectrometry for Drug Metabolism Studies
CRC Press ISBN: 0849319633 2004-12-17 PDF 370 pages 10.0 Mb RS

Mass spectrometry (MS) is fast becoming the premier tool for analyzing various drug metabolism samples in the early phases of drug discovery and research. Introducing the newer, more powerful MS equipment and exploring new applications for using them, this book provides a state-of-the-art look at this promising field. Using Mass Spectrometry for Drug Metabolism Studies is an excellent resource for professionals in the fields of mass spectrometry and drug metabolism. It offers current knowledge in stand-alone chapters that address specific topics thoroughly enough to be read independently, with notes and references to other chapters for further reading. The first eight chapters discuss current topics regarding the use of MS for analyzing various types of in vitro and in vivo drug metabolism samples and the final four chapters describe the latest MS technology and its uses. In each chapter, expert authors demonstrate how to apply MS to determine drug metabolism parameters. They also explain the different drug metabolism concepts and their importance. Although there are a few books currently on the market that address this topic, they are rapidly becoming out-of-date. This book gives drug researchers and pharmacokineticists the latest information available on this important technology.

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BioNanotechnology 2007

2009-01-14T23:51:00.000+02:00

BioNanotechnology by Elizabeth Papazoglou
Morgan and Claypool Publishers ISBN 1598291386 2007-08-21 PDF 139 Pages 4.6 MB

This book aims to provide vital information about the growing field of bionanotechnology for undergraduate and graduate students, as well as working professionals in various fields. The fundamentals of nanotechnology are covered along with several specific bionanotechnology applications, including nanobioimaging and drug delivery which is a growing $100 billions industry. The uniqueness of the field has been brought out with unparalleled lucidity; a balance between important insight into the synthetic methods of preparing stable nano-structures and medical applications driven focus educates and informs the reader on the impact of this emerging field. Critical examination of potential threats followed by a current global outlook completes the discussion. In short, the book takes you through a journey from fundamentals to frontiers of bionanotechnology so that you can understand and make informed decisions on the impact of bionano on your career and business.

CONTENTS

Introduction
0.1 Bionanotechnology: A Historical Perspective
0.2 Nanotechnology and Bionanotechnology
0.3 Notable Nanoimages in Bionanotechnology
0.3.1 AFM-Qd
0.3.2 Nano-drug Delivery Chip
0.3.3 Atomic Force Microscopy Image (AFM) of SWNT
0.3.4 Scanning Electron Microscopy Image (SEM) of SWNT
0.4 Opportunities and Challenges of Bionanotechnology
0.5 Growth potential of Nanotechnology and Related Expenditures
References

1. The Significance of Nano Domain
1.1 Limitations of Micron Size
1.2 Need for Nano-Size—Surface Volume Ratio Significance
1.3 Significance and Key Features of Nano-Size
1.4 Derivation of Bohr’s Atomic Radius of a Hydrogen Atom
1.5 Comparison of Particle Behavior at Nano-Size to Macro Size: Gold and Titania
1.6 Advantages of Scaling Down—Nano-Size
References

2. Nano Drug Delivery
2.1 Conventional Drug Delivery
2.1.1 First Pass Effect
2.1.2 Routes of Delivery
2.2 Targeted Drug Delivery
2.3 Chemistry of Drug Delivery Vehicles
2.3.1 Nanocapsules
2.3.2 Unilamellar Liposomal Vesicles
2.3.3 Nanoparticles
2.3.4 Microemulsions
2.4 Delivery Profiles
2.4.1 Rate-Preprogrammed Drug Delivery Systems
2.4.2 Activation-Modulated Drug Delivery Systems
2.4.3 Feedback-Regulated Drug Delivery Systems
2.4.4 Site-Targeting Drug Delivery Systems
2.5 The Role of Nanotechnology in Drug Delivery
2.5.1 Transdermal
2.5.2 Blood Brain Barrier
2.6 Advantages of Targeted Drug Delivery Systems
References

3. BioNanoimaging
3.1 Quantum Dots
3.2 Ultrasound Contrast Agents
3.3 Magnetic Nanoparticles
References

4. Successful Applications of Bionanotechnology
4.1 Nanostructures and Nanosystems
4.1.1 Nanopore Technology
4.1.2 Nano Self-Assembling Systems
4.1.3 Cantilevers
4.1.4 Nanoarrays
4.2 Nanoparticles
4.2.1 Quantum Dots (QDs)
4.2.2 Paramagnetic Iron Oxide Crystals
4.2.3 Dendrimers
4.2.4 Carbon Nanotubes
4.2.5 Nanosomes and Polymersomes
4.3 In Vitro Diagnostics
4.4 Medical Application of Nanosystems and Nanoparticles
4.4.1 Drug Delivery Applications
4.4.2 Nanoparticles in Molecular Imaging
4.5 Summary and Conclusions
References

5. Synthesis of Gold, Titania, and Zinc Oxide
5.1 Synthesis of Gold
5.1.1 Background
5.1.2 Brust Method of Synthesis of Thiol Derivatized Gold NPs by Biphasic Reduction
5.1.3 Gold Colloids
5.1.4 Gold Nanofilm
5.1.5 Gold Nanorods
5.2 Synthesis of Titania Nanostructures
5.2.1 Background
5.2.2 Solvo-Thermal Synthesis of Titania Nano Crystals
5.2.3 Sol-Gel Template Synthesis of Titania Nano Tubes and Rods
5.2.4 Overview of Other Synthesis Methods
5.3 Synthesis of Zinc Oxide
5.3.1 Background
5.3.2 The Solid-Vapor Synthesis of ZnO
5.1
5.1.1 Brust Method of Synthesis of Thiol Derivatized Gold NPs by Biphasic Reduction
5.2
5.2.1 Solvo-Thermal Synthesis of Titania Nano Crystals
5.2.2 Sol-Gel Template Synthesis of Titania Nano Tubes and Rods
5.2.3 Overview of Other Synthesis Methods
5.3
5.3.1 The Solid-Vapor Synthesis of ZnO: Horizontal Tube Furnace
5.3.2 Wurtzite Structure of ZnO
References

6. Is Bionanotechnology a Panacea?
6.1 Background
6.2 Primary Concerns
6.3 Assessing Potential Risks
6.3.1 Inhalation
6.3.2 Contact/Dermal Delivery
6.3.3 Other Routes of Contact
6.3.4 Environmental Impacts of NPs and the Food Chain
6.3.5 Explosion Hazards
6.4 Lessons from the Past
6.5 Conclusion
References

7. Roadmap to Realization of Bionanotechnology
7.1 Introduction
7.2 Nano Vision: the Futuristic Goals of Bionanotech
7.3 Working toward Realization: Current Progress
7.4 Screenshot of Reality: Bionano-Unbiased/Uncensored
7.5 The Nano Mission: Roadmap to Realization of Translation Research
7.5.1 Bionano in the US
7.5.2 Bio-Nano in Japan
7.5.3 Bio-Nano in UK
7.5.4 UK–Japan Joint Initiative for Bionanotechnology
7.5.5 The EU Initiative in Bionanotech
7.5.6 Bionano in Asia

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Biopharmaceutics Applications in Drug Development

2009-01-14T23:48:00.001+02:00

In the last two decades, the discipline of biopharmaceutics has undergone considerable advances, particularly with regard to bioavailability and bioequivalence as they relate to product quality and regulatory standards of approval. Textbooks in the field have not been able to keep up with the growth of current and emerging applications of regulatory aspects of biopharmaceutics.

Biopharmaceutics Applications in Drug Development fills this gap. This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.

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Stahl - Essential Psychopharmacology. Neuroscientific Basis and Practical Applications - 2nd. Ed.

2009-01-14T23:45:00.001+02:00

Stephen M. Stahl, "Essential Psychopharmacology. Neuroscientific Basis and Practical Applications"
Publisher: Cambridge University Press ISBN-10: 0521646154 2nd. Ed. 2000 PDF 660 pages English 48,5 MB

Stahl's Essential Psychopharmacology has established itself as the preeminent source of education and information in its field. This much expanded second edition enlists advances in neurobiology, and recent clinical developments, to explain with renewed clarity the concepts underlying drug treatment of psychiatric disorders. New neurotransmitter systems, new theories on schizophrenia, clinical advances in antipsychotic and antidepressant therapy, new coverage of attention deficit disorder, sleep disorders and drug abuse, and a new chapter on gender and sexual psychopharmacology - these are all features of this edition. The fully revised text is complemented by many new illustrations, instructive and entertaining as before, and enhanced to reflect new knowledge and topics covered for the first time. The illustrations and their captions may be used independently of the main text for a rapid introduction to the field or for review, and self-assessment tests follow each chapter. Even more, this will be the essential text for students, scientists, psychiatrists and other mental health professionals, enabling them to master the complexities of psychopharmacology, and plan sound treatment approaches based on current knowledge.

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Color Atlas of Genetics

2009-01-14T23:42:00.000+02:00

Color Atlas of Genetics
Thieme Medical Publishers ISBN:0865779589 Edition - 2001 PDF 486 pages 28MB rapidshare

A remarkable achievement by a single author...concise but informative...No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition." --American Journal of Medical Genetics More than ever, a solid understanding of genetics is a fundamental element of all medical and scientific educational programs, across virtually all disciplines. And the applications--and implications--of genetic research are at the heart of current medical scientific debates. Completely updated and revised, The Color Atlas of Genetics is an invaluable guide for students of medicine and biology, clinicians, and anyone else interested in this rapidly evolving field. With more than 200 absorbing full-color plates concisely explained on facing pages, the atlas offers readers an easy-to-use, yet remarkably detailed guide to key molecular, theoretical, and medical aspects of genetics and genomics. Brief descriptions of numerous genetic diseases are included, with references for more detailed information. Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most advanced applications.

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Six Sigma in the Pharmaceutical Industry: Understanding, Reducing, and Controlling Variation in Pharmaceuticals and Biologics

2009-01-14T23:37:00.001+02:00

Features:

Describes the concept of reducing and controlling variation with the Six Sigma method specifically for the pharmaceutical industry
Provides case studies, charts and critical reviews of data to illustrate the concepts
Discusses practical applications within the pharmaceutical industry
Highlights regulatory compliance issues
Includes a one-point-learning summary and references at the end of each chapter
Contents
1. The Enormous Initial Mistake
2. The Origins of Six Sigma
3. Evolution
4. Revolution
5. Paradox
6. Close Enough; … Or On Target?
7. Make More…Faster!
8. Case Studies
9. The Camera Always Lies
10. Keeping It Simple
11. Why Use Control Charts?
12. Average and Range Control Charts
13. Origins and Theory
14. Charts for Individuals
15. Practical Considerations
16. Improving Laboratories
17. Beyond Compliance
Appendix
Index

Six Sigma in the Pharmaceutical Industry is the first book to introduce the fundamentals of Six Sigma, examine control chart theory and practice, and explain the concept of variation management and reduction applied specifically to the pharmaceutical industry. The first half lays out a conceptual framework for understanding variation, while the second half introduces control chart theory and practice. Using case studies and statistics, the book illustrates the concepts and explains their application to actual workplace improvements. Providing the basis for a complete operating philosophy, this book focuses on core concepts and their implementation to improve the existing products and processes in the pharmaceutical industry.

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Biochemistry

2009-01-14T23:35:00.000+02:00

Biochemistry
W. H. Freeman ISBN:0716746824 Fifth Edition - 2002 PDF 1514 pages 25.6 MB

For more than 25 years, and through four editions, Stryer's Biochemistry has laid out this beautiful subject in an exceptionally appealing and lucid manner. The engaging writing style and attractive design have made the text a pleasure for our students to read and study throughout our years of teaching. Thus, we were delighted to be given the opportunity to participate in the revision of this book. The task has been exciting and somewhat daunting, doubly so because of the dramatic changes that are transforming the field of biochemistry as we move into the twenty-first century. Biochemistry is rapidly progressing from a science performed almost entirely at the laboratory bench to one that may be explored through computers. The recently developed ability to determine entire genomic sequences has provided the data needed to accomplish massive comparisons of derived protein sequences, the results of which may be used to formulate and test hypotheses about biochemical function. The power of these new methods is explained by the impact of evolution: many molecules and biochemical pathways have been generated by duplicating and modifying existing ones. Our challenge in writing the fifth edition of Biochemistry has been to introduce this philosophical shift in biochemistry while maintaining the clear and inviting style that has distinguished the preceding four editions.

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Molecular Nutrition and Genomics: Nutrition and the Ascent of Humankind

2009-01-14T23:34:00.001+02:00

Molecular Nutrition and Genomics: Nutrition and the Ascent of Humankind
Stationary Office Pages: 140 2007-07-09 ISBN: 0470081597 15 MB

This fascinating book draws it subject matter from a range of relevant disciplines that extend from molecular nutrition, nutritional sciences, and nutrition dietetics through to genetics, genomics, and anthropology. It presents a vital portrait of the absolutely fundamental role that nutrition has played and continues to play in shaping who and what human beings are, as well as where they evolved from, and where they may be heading as a species.

Molecular Nutrition: Nutrition and the Evolution of Humankind:

* Blends coverage of the molecular mechanisms that underpin nutrient-gene interactions with evolutionary theory
* Takes a molecular biological approach to problem solving, and moves nutrition away from its dietetic and anthropological origins to the front lines of genomic research
* Covers key concepts in molecular biology; the –omics revolution and bioinformatics; recent human evolution; molecular mechanisms of gene-nutrient interactions; the importance of nutrients and genomics in disease; the evolution of micronutrient metabolism, protein structure, and human disease; nutrients and the human lifecycle; contemporary dietary patterns; leading-edge laboratory tools in nutrigenomics and human evolutionary studies

Written by an internationally recognised expert in the field, Molecular Nutrition: Nutrition and the Evolution of Humankind is an invaluable text and reference book for a wide range of teachers, students, and researchers.

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Chronic Myeloid Leukemia

2009-01-14T23:22:00.000+02:00

Chronic Myeloid Leukemia (US$149.95)
Stationary Office Pages: 176 2006-12-13 ISBN: 0849379555 3 MB

Chronic Myeloid Leukemia (CML) remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level and has been used by researchers to develop a variety of therapies and therapeutic assessment methods. This concise, readable guide assembles and synthesizes the latest developments and trends in the treatment of CML and provides an authoritative and convenient summary of the latest progress in imatinib trials, the molecular monitoring of CML responses, and the engineering of new therapies to overcome resistance and improve patient care.

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Pharmacokinetics and Metabolism in Drug Design

2009-01-13T02:03:00.001+02:00

Dennis A. Smith, "Pharmacokinetics and Metabolism in Drug Design"
Wiley-VCH January 9, 2001 ISBN: 3527301976 160 pages PDF 2 MB

The medical benefits of a drug are not only dependent on its biological effect, but also on its "life cycle" within the organism - from its absorption into the blood, distribution to tissue until its eventual breakdown or excretion by the liver and kidneys.

Here, the authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. The authors cover everything from the fundamental principles right up to the latest developments using high throughput methods to analyze the pharmacokinetic properties of active substances.
Particular emphasis is placed on the impact of pharmacokinetic parameters on the discovery of new drugs - one of the most challenging tasks in global pharmaceutical research.
Thus, this book is aimed at all those dealing professionally with the development and application of pharmaceutical substances. Furthermore, the readily comprehensible style of writing makes it equally suitable for students of pharmacy and related subjects, who feel that pharmacokinetics is covered too briefly in the standard textbooks.

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Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications

2009-01-13T02:02:00.000+02:00

Andrea Bonetti, Roberto Leone, Franco Muggia, Stephen B. Howell, “Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications”
Humana Press 2008-12-18 ISBN: 1603274588 390 pages PDF 12 MB

Following the serendipitous discovery of cisplatin by Barnett Rosenberg back in 1965 and its approval in 1978 by the Food and Drug Administration, a growing number of platinum compounds have emerged as fundamental components for the treatment of different types of cancer. Although replaced by the better tolerated analogue carboplatin, cisplatin itself is still an important tool for the treatment of germ cell tumors and cancers of head and neck. The introduction into the clinic of the DACH platinum compound oxaliplatin has broadened the spectrum of activity of the platinums to gastro-intestinal cancers, and especially colorectal cancer. Among the newer analogues on the way to the clinic, satraplatin is particularly interesting since it is the first orally available platinum analogue. The purpose of this book is to cover the most important issues related to platinum drugs including the mechanisms of action and resistance; the development of novel platinum compounds and other metal coordination compounds; the combination of platinum drugs with targeted therapies for the treatment of common malignancies such as breast, colorectal, lung and gynaecologic cancers; new therapeutic indications in prostate and genitourinary tumours; integration with radiotherapy; special therapies such as intraperitoneal administration; pharmacodynamic-based dosing; management of anaemia and myelosuppression; mechanisms of neurotoxicity and its protection.

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Nitroxides: Applications in Chemistry, Biomedicine, and Materials Science

2009-01-13T01:59:00.000+02:00

Gertz Likhtenshtein, Jun Yamauchi, Shin'ichi Nakatsuji, Alex I. Smirnov, Rui Tamura, “Nitroxides: Applications in Chemistry, Biomedicine, and Materials Science”
Wiley-VCH 2008-04-18 ISBN: 3527318895 438 pages PDF 3,2 MB

Covering all aspects of this field, this volume also critically discusses recent results obtained with the use of nitroxides, while providing an analysis of future developments.
Written by a group of scientists with long-term experience in investigating the chemistry, physicochemistry, biochemistry and biophysics of nitroxides, the book is not intended as an exhaustive survey of each topic, but rather a discussion of their theoretical and experimental background, as well as recent advances.
The first four chapters expound the general theoretical and experimental background and the advantages of modern ESR technique. Chapter 5 focuses on fundamentals and recent results in the preparation and basic chemical properties, while the next two chapters briefly outline principles and current results in nitroxides as spin probes, and as redox probes and spin traps. These chapters form the basis for the subsequent more detailed studies of nitroxides in physicochemistry, while the final chapters concentrate on the advantages of magnetic materials on the basis of nitroxides. Finally, the concluding chapter considers the rapidly developing field of biomedical, therapeutic and clinical applications.
With more than 1,100 references to essential literature, this volume provides fundamental knowledge of instrumentation, data interpretation, capacity and recent advantages of nitroxide applications, allowing readers to understand how nitroxides can help them in solving their own problems.

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Encyclopedia of Biopharmaceutical Statistics

2009-01-13T01:50:00.000+02:00

Shein-Chung Chow, “Encyclopedia of Biopharmaceutical Statistics”
Informa HealthCare 2003-06-04 ISBN: 0824742613 1000 pages PDF 57,2 MB

Millennium Pharmaceuticals, Cambridge, MA. Resource offers more than 3,300 lists expanded to reflect amendments to regulatory requirements and recently developed statistical methods impacting the drug review/approval process and biopharmaceutical research and development. Offers more than 3,000 equations, tables, and figures.

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New Therapeutic Agents In Thrombosis And Thrombolysis

2009-01-13T01:47:00.000+02:00

New Therapeutic Agents In Thrombosis And Thrombolysis
Publisher: CRC 1997-01-15 ISBN: 082479866X Pages: 681 31 MB

Focusing on pharmaceutical agents that have advanced to Phase II of clinical testing or that hold significant promise in the field of therapeutics, this up-to-date resource provides a comprehensive review of the basic mechanisms, clinical developments, and applications of new therapeutic agents in thrombosis and thrombolysis.

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Treatments from Toxins - The Therapeutic Potential of Clostridial Neurotoxins

2009-01-13T01:45:00.000+02:00

Treatments from Toxins - The Therapeutic Potential of Clostridial Neurotoxins
CRC PRESS, 2007 ISBN: 9780849327094 K. Foster English 318p. 5.5 MB

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A Manager's Guide to the Design and Conduct of Clinical Trials

2009-01-13T01:44:00.000+02:00

A Manager's Guide to the Design and Conduct of Clinical Trials
Pages: 248 Date: 2002 ISBN: 0471226157 Rared PDF File Rapidshare & Depositfiles 2 MB

This engaging and non-technical guide to clinical trials covers issues study design, organization, management, analysis, recruitment, reporting, software, and monitoring. Free from the jargon-laden treatment of other books, A Manager’s Guide to the Design and Conduct Clinical Trials is built upon the formula of first planning, then implementing, and finally performing essential checks.

Offers an executive level presentation of managerial guidelines as well as handy checklists accompanied by extracts from submitted protocols
Includes checklists, examples, and tips, as well as a useful appendix on available software Covers e-submissions and use of computers for direct data acquisition
Incorporates humorous yet instructive and true anecdotes to illustrate common pitfalls

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Antiepileptic Drugs: Combination Therapy and Interactions

2009-01-13T01:40:00.000+02:00

Antiepileptic Drugs: Combination Therapy and Interactions
Pages: 514 Date: 2005 ISBN:052182219X Rared PDF File Rapidshare & Depositfiles 2 MB

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians , psychiatrists and general practitioners.

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Julius A. Vida - Androgens and Anabolic Agents

2009-01-12T01:40:00.001+02:00

Julius A. Vida - Androgens and Anabolic Agents
Academic Press Inc.,U.S. July 1969 ISBN: 0127218505 328 pages PDF 112 MB

This book is a classic, but you will be very hard up to find it anywhere as it is long out of print. If you have an interest in the science of this topic regardless of whether it is medical or athletic it is a must have. Dr. Vida really put a lot of research and useful explanations in this one. Highly suggested reading.

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Polymeric drugs & drug delivery systems by Ottenbrite

2009-01-12T01:38:00.002+02:00

Polymeric Drugs & Drug Delivery Systems by Ottenbrite
Publisher: CRC Press ISBN: 1566769566 2001 Pages: 313 PDF 8.9 MB

The book contains 22 chapters and covers a very wide range of topics. With a few exceptions, these contributions are from leaders in the field of drug delivery. The ideas and results presented are all extremely creative and interesting. This reviewer would recommend this book as it presents a broad selection of some very interesting directions that polymer drug delivery will be taking in the near future. - Lisa Brannon-Peppas, PhD, The Department of Biomedical Engineering, The University of Texas at Austin

Product Description
Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensor sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume publishes consists of twenty-two recent research-based reports reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports were prepared by top scientists in the field and are based on current research conducted at leading laboratoriesresearch organizations in the U.S.A., Europe, and Far EastAsia. These 22 chaptersThese 22 chapters report the latest information in the application of polymers to biological systems.

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_drug_delivery_systems_by_Ottenbrite__7E2001_7E.pdf

FASTtrack: Managing Symptoms in the Pharmacy

2009-01-12T01:32:00.000+02:00

Alan Nathan, “FASTtrack: Managing Symptoms in the Pharmacy”
Pharmaceutical Press 2007-11-30 ISBN: 0853697272 233 pages PDF 2,05 MB

This is a revision guide for students giving bullet points of basic information on managing symptoms in the pharmacy."Fast Track" is a new series of indispensable revision guides created especially for undergraduate pharmacy students.The content of each title focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs, case studies, sample essay questions and worked examples."The Fast Track" series provides the ultimate lecture notes and is a must-have for all pharmacy undergraduate students wanting to revise and test themselves for forthcoming exams.Covering all common ailments, organized by system in alphabetical order, this book provides all the essential information needed for managing symptoms presented in the pharmacy.A Fast Track website will also be live at time of publication and will include MCQs, and samples.

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Fragment-Based Drug Discovery: A Practical Approach

2009-01-12T01:29:00.000+02:00

Edward Zartler, Michael Shapiro, “Fragment-Based Drug Discovery: A Practical Approach”
Wiley 2008-12-31 ISBN: 0470058137 296 pages PDF 3,4 MB

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery.

Fragment-Based Drug Discovery: A Practical Approach is a guide to the techniques and practice of using fragments in drug screening. The emphasis is on practical guidance, with procedures, case studies, practical tips, and contributions from industry. Topics covered include:
an introduction to fragment based drug discovery, why using fragments is a more efficient process than predominant models, and what it means to have a successful FBDD effort.
setting up an FBDD project
library building and production
NMR in fragment screening and follow up
application of protein-ligand NOE matching to the rapid evaluation of fragment binding poses
target immobilized NMR screening: validation and extension to membrane proteins
in situ fragment-based medicinal chemistry: screening by mass spectrometry
computational approaches to fragment and substructure discovery and evaluation
virtual fragment scanning: current trends, applications and web based tools
fragment-based lead discovery using covalent capture methods
case study from industry: the identification of high affinity beta-secretase inhibitors using fragment-based lead generation

With contributions from industry experts who have successfully set up an industrial fragment-based research program, Fragment-Based Drug Discovery: A Practical Approach offers essential advice to anyone embarking on drug discovery using fragments and those looking for a new approach to screening for drugs.

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Ophthalmic Drug Delivery Systems, Second Edition

2009-01-10T05:07:00.002+02:00

Extensively revised and updated, this second edition compares conventional and innovative drug delivery systems. The book covers significant ophthalmic advances and breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery. It examines procedures in pharmacokinetic/pharmacodynamic modeling for the determination of appropriate dosing regimens, covers new developments in animal modeling, and discusses current regulations governing patenting, commercial product release, and human testing. This in-depth reference lays the groundwork for overcoming constraints on the delivery of ophthalmic drugs.

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Pathology and Therapeutics for Pharmacists, 3rd Edition

2009-01-10T05:07:00.001+02:00

Pathology and Therapeutics for Pharmacists, 3rd Edition
By Russell J. Greene, Norman D. Harris

Publisher: Pharmaceutical Press

Number Of Pages: 982
Publication Date: 2008-02-28
ISBN-10 / ASIN: 085369690X
ISBN-13 / EAN: 9780853696902
Binding: Paperback
This is the textbook for undergraduate pharmacists which takes an integrated approach to the pathophysiological and pharmacotherapeutic principles underlying the treatment of disease. This new edition of "Pathology and Therapeutics for Pharmacists" has been completely revised and updated to reflect advances in therapeutic practice and in the understanding of many disease states. Taking an integrated approach to the pathophysiological and pharmacotherapeutic principles underlying the treatment of disease, it is based on many years' experience of teaching one of the pioneering undergraduate clinical pharmacy courses in the UK. "Pathology and Therapeutics for Pharmacists" is an essential textbook for undergraduate pharmacists and should be of considerable interest to practising pharmacists and other healthcare professionals. Changes to the third edition include: a new chapter on haematological disease; incorporation of evidence based national and international therapeutic guidelines; the addition of thyroid disease in the endocrine chapter; a thoroughly revised chapter on pathological processes; and, re-ordered chapters to reflect British National Formulary sequence.

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Principles of Clinical Pharmacology, Second Edition

2009-01-10T05:04:00.001+02:00

Publisher: Academic Press
Number Of Pages: 568
Publication Date: 2006-09-20
ISBN-10 / ASIN: 0123694175
ISBN-13 / EAN: 9780123694171
Binding: Hardcover

Book Description:

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists.

* Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy.
* Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course.
* Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study.
* Wide-ranging perspective of authors drawn from the ranks of Federal agencies,academia and the pharmaceutical industry.
* Expanded coverage of pharmacogenetics
* Expanded coverage of drug transporters and their role in interactions
* Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions
* A new chapter on drug discovery that focuses on oncologic agents
* Inclusion of therapeutic antibodies in chapter on biotechnology products

Summary: Excellent resource for post-graduate training
Rating: 5

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Phytochemicals: Nutrient-Gene Interactions

2009-01-10T05:00:00.001+02:00

By
Publisher: CRC
Number Of Pages: 232
Publication Date: 2006-02-22
Sales Rank: 1058083
ISBN / ASIN: 0849341809
EAN: 9780849341809
Binding: Hardcover
Book Description:
Phytochemicals: Nutrient-Gene Interactions analyzes the mechanisms of action and impact of phytochemical-gene interactions on health, aging, and disease. The book covers experimental methodologies for identifying significant interactions between diet, genetic variants, and different markers of cardiovascular disease, inflammation, and obesity. It explores the role of resveratrol in cardiovascular health; the preventative mechanisms of whole grains and omega-3 fatty acids; epidemiological research on plant-based foods; the non-antioxidant cellular properties of vitamin E; and controlled clinical trials. The book illustrates the growing role of nutrigenomics in the responsible development of safe and effective phytochemical products within the food, pharmaceutical, and supplement industries.

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the Constituents of Medicinal Plants

2009-01-10T04:58:00.001+02:00

Constituents of Medicinal Plants: An introduction to the chemistry and therapeutics of herbal medicine
ISBN: 0851998070Author: Kerry BonePublisher: CABI Publishing

Easy to understand introduction to the chemistry of medicinal plants
Includes over 100 diagrams
Refers to original research studies and clinical trials
Refers to plants commonly used by herbalists throughout Europe, North America and Australasia

**
During recent years herbal medicine has become an increasingly scientifically based system of healing. Due to demands from both the public and medical establishments, studies leading to the scientific explanation of plant therapeutic capabilities are allowing this practice to gain increasing credibility and acceptance within the medical community.

This book provides an introduction to the complex area of plant constituents and the therapeutic activities associated with them.

Introduction to phytochemistry
Phenols
Polyphenols-tannins and flavonoids
Glycosides
Terpenes
Triterpenoids and saponins
Essential oils and resins
Fixed oils and alkamides
Polysaccharides
Alkaloids

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Pharmaceutical Guidelines

2009-01-06T22:42:00.002+02:00

Common Technical Document:
ASEAN
ICH

GMP -Drug Product:
INDIA
PIC
USFDA
WHO

GMP-Drug substances:
ICH
PIC
USFDA
WHO

ICH Guidelines:
Efficacy
Multidisciplinary
Quality
Safety

Regulatory Audits:
PIC
WHO

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HIV/AIDS: A Very Short Introduction

2009-01-06T22:38:00.001+02:00

Alan Whiteside, “HIV/AIDS: A Very Short Introduction”
Oxford University Press, USA 2008-02-25 ISBN: 0192806920 144 pages PDF 1,6 MB

HIV/AIDS is without doubt the worst epidemic to hit humankind since the Black Death. As of 2004 an estimated 40 million people were living with the disease, and about 20 million had died. Despite rapid scientific advances there is still no cure and the drugs are expensive and toxic. In the developing world, especially in parts of Africa, life expectancy has plummeted to below 35 years, causing a serious decline in economic growth, a sharp increase in orphans, and the imminent collapse of health care systems. The news is not all bleak though. There have been unprecedented breakthroughs in understanding diseases and developing drugs. Because the disease is so closely linked to sexual activity and drug use, the need to understand and change behavior has caused us to reassess what it means to be human and how we should operate in the globalizing world. This Very Short Introduction tackles the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease, and suggests how we must respond.

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Textbook of Pharmacoepidemiology (2007)

2009-01-06T22:35:00.000+02:00

Textbook of Pharmacoepidemiology
Publisher: Wiley Language: English ISBN: 0470029250 518 pages Data: 2007 PDF 3 Mb

Description: The Textbook of Pharmacoepidemiology provides a streamlined text for evaluating the safety and effectiveness of medicines. It includes a brief introduction to pharmacoepidemiology as well as sections on data sources, methodology and applications. Each chapter includes key points, case studies and essential references.

* One-step resource to gain understanding of the subject of pharmacoepidemiology at an affordable price
* Gives a perspective on the subject from academia, pharmaceutical industry and regulatory agencies
* Designed for students with basic knowledge of epidemiology and public health
* Includes many case studies to illustrate pharmacoepidemiology in real clinical setting

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Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet

2009-01-06T22:32:00.001+02:00

Alan Crozier "Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet"
Wiley-Blackwell 2006-12-11 ISBN: 1405125098 384 pages PDF 9 MB

Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet covers the main groups of natural products from a chemical and biosynthetic perspective with illustrations of how genetic engineering can be applied to manipulate levels of secondary metabolites of economic value as well as those of potential importance in diet and health. These descriptive chapters are augmented by chapters showing where these products are found in the diet, how they are metabolized and reviewing the evidence for their beneficial bioactivity.

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Medicinal Applications of Coordination Chemistry

2009-01-06T22:27:00.000+02:00

Medicinal Applications of Coordination Chemistry By Chris Jones, John R. Thornback
Publisher: Royal Society of Chemistry ISBN: 0854045961 2007 PDF 290 pages 6 Mb rared PDF

Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications.

Medicinal Applications of Coordination Chemistry begins with a brief historical review and an introduction to the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Key sections include diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds.

This book is ideal for researchers in academia and industry and comes complete with examples of real life applications.

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Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

2009-01-06T22:23:00.001+02:00

by III, Robert O. Williams, David R. Taft, Jason T. McConville

Advanced Drug Formulation Design to Optimize Therapeutic Outcomes demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states.
This book discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targeting of drugs, especially poorly water soluble drugs to provide enhanced therapeutic outcomes. In addition, it highlights areas of therapy showing the most promise for improvement in clinical outcomes via advanced formulation design.
Features
addresses numerous advanced formulation and delivery technologies, including mucoadhesion, chronopharmaceutical delivery through smart delivery devices, targeted nanoparticle systems, and advanced solubilization technologies with liposomal delivery
covers major therapeutic categories such as infectious disease, cancer, CNS disorders, and endocrine disorders
includes pre-clinical or clinical evidence, showing an enhanced therapy achieved with advanced formulation design
discusses difficult-to-treat tumors requiring chemotherapeutic agents to pass the blood brain barrier, which is of particular interest for improving the overall efficacy of such drugs with severe side-effects when administered in high doses
Partial Table of Contents
Part 1: Infectious Diseases
Pulmonary Infections
Oral Infections
Systemic Infections
Ophthalmic Infections
Part 2: Oncology
Targeted Nanoparticle Systems for Cancer Therapy
Systemic Delivery of Anti-cancer Agents
Cancer and the Blood Brain Barrier
Part 3: Transplantation
Immunosuppression for Transplantation Patients
Systemic Delivery of Immunosuppressants
Targeted Delivery of Immunosuppresants
Part 4: Other Therapies
Trans-Mucosal Delivery
CNS Diseases
Endocrinological Diseases
Index

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An atlas of schizophrenia. By Stefan Martin, Travis Mike, Murray Robin

2009-01-06T22:22:00.000+02:00

Stefan Martin, Travis Mike, Murray Robin. An atlas of schizophrenia
(The encyclopedia of visual medicine series)
CRC Press LLC 2002 ISBN: 1850700745 89 pages PDF 5 Mb rar

Schizophrenia is a puzzle. An atlas is probably not the most obvious format for a book on schizophrenia but the authors have succeeded in producing a useful and interesting one.

Schizophrenia is a puzzle. Emil Kraepelin considered that his life's work had resulted merely in progress in understanding the psychoses, not a solution. Gottesman and Shields regarded the causes of schizophrenia as being an epigenetic puzzle, an analogy that continues to serve us well. Research in this area seems to produce ever more pieces, rather than fitting them together.

Diagrams, tables and figures give contemporary views an immediate impact, with modern techniques of investigation, such as neuroimaging, being particularly well suited to this format. These are balanced by the paintings from the Bethlem Royal Hospital Archives and Museum that entertain and fascinate alongside the factual information: they give an impression of the human as well as scientific and psychiatric aspects of schizophrenia.

Thus, the book provides a useful map for all.

TOC
1 Clinical features
2 Epidemiology and risk factors
3 Pathogenesis
4 Neurochemistry and pharmacotherapy
5 Psychosocial treatment

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Pharmaceutical Compounding and Dispensing

2009-01-06T22:17:00.001+02:00

This is a revision guide for students giving bullet points of basic information on pharmaceutical compounding and dispensing followed by questions and answers."Fast Track" is a new series of indispensable revision guides created especially for undergraduate pharmacy students.The content of each title focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs, case studies, sample essay questions and worked examples."The Fast Track" series provides the ultimate lecture notes and is a must-have for all pharmacy undergraduate students wanting to revise and test themselves for forthcoming exams.Based on the successful textbook, "Pharmaceutical Compounding and Dispensing", this book has been designed to assist the student compounder in understanding the key dosage forms encountered within extemporaneous dispensing.A Fast Track website will also be live at time of publication and will include MCQs, sample online content and much more.

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Nuclear Receptors in Drug Metabolism

2009-01-06T22:14:00.002+02:00

Nuclear Receptors in Drug Metabolism
By Wen Xie
Publisher: Wiley
Number Of Pages: 330
Publication Date: 2008-11-03
ISBN-10 / ASIN: 0470086793
ISBN-13 / EAN: 9780470086797
Binding: Hardcover :

Providing an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development, this book equips drug development scientists with an interdisciplinary understanding of these receptors and how to regulate them. This aids in pharmaceutical research to target drugs and treat diseases like cancer, coronary heart disease, and diabetes. A single source for researchers, this book collects material otherwise scattered among journals, and adds background and applications data to make the chapters more comprehensive.

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Fundamental Toxicology

2009-01-06T22:14:00.001+02:00

Fundamental Toxicology
Publisher: Royal Society of Chemistry 2006-03-27 ISBN: 0854046143 Pages: 462 PDF 3.4 MB

Product Description:
A-Z of Emergency Radiology is aimed at trainee and practising radiologists, as well as all other healthcare professionals involved in interpreting scans of all imaging modalities in the emergency room setting. It provides a simple, easily accessible guide to the key aspects of the most commonly encountered problems. The simple A-Z format of the book allows the reader to look up the key features of a known condition, or to quickly confirm a suspected diagnosis.

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Antimicrobial/Anti-Infective Materials: Principles and Applications

2009-01-06T22:11:00.000+02:00

Antimicrobial/Anti-Infective Materials: Principles and Applications
By Samuel P. Sawan, Gurusamy Manivannan
Publisher: CRC
Number Of Pages: 346
Publication Date: 1999-12-10
ISBN-10 / ASIN: 1566767946
ISBN-13 / EAN: 9781566767941
Binding: Hardcover
As our consciousness of microbes increases, it appears that our desire to control our interactions with germs also increases in proportion. This is clearly demonstrated by examining the incredible growth in the number and sales volume of consumer products with antimicrobial claims. In the medical field as well, there is much interest in the use of antimicrobial/anti-infective materials for medical devices and general healthcare applications. Antimicrobial/Anti-Infective Materials: Principles, Applications and Devices represents the best current research and practice on ways to reduce infection caused by devices inserted into the human body. This volume presents important recent developments in the research, development, and applications of anti-infective materials for use in medical devices. It includes 15 in-depth reports by more than 40 leading specialists in biomaterials and medical devices that cover a wide range of important advances in various materials and applications. These include improved coatings and surface modifications techniques, improved materials designed for inherent infection resistance, and applications in the areas of cardiac, orthopedic, ENT, and vascular devices. This book serves the information needs of all those involved in the research, development, design, and selection of biomaterials and medical devices. It will benefit anyone who designs, uses, and monitors anti-infective materials, as well as those who develop and apply products made from these materials.

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Mass Spectrometry in Drug Metabolism and Pharmacokinetics

2009-01-06T22:03:00.002+02:00

Mass Spectrometry in Drug Metabolism and Pharmacokinetics
By Ragu Ramanathan
Publisher: Wiley
Number Of Pages: 390
Publication Date: 2008-12-31
ISBN-10 / ASIN: 0471751588
ISBN-13 / EAN: 9780471751588
Binding: Hardcover

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.

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Your Pharmacy work Manager , The Orchid Medical Spa 6.11

2009-01-05T03:24:00.004+02:00

Orchid Medical Spa Software has the most powerful and simple appointments database for management of your medi-spa. Adding or editing medi-spa appointments is simple. See your appointment management menu. Just click on the time slot on the appointment book and Orchid Medical Spa Software does the rest! Customized color codes make it easy to quickly view when an employee is available to service a client. The Orchid Medical Spa Software screen shots appointment management menu offers diverse, yet proficient medi-spa options.

Features Overview with Orchid Medical Spa Software

Orchid Medical Spa 6.1.1 44,5 MB

Appointments
View any day's schedule in easy- to- read format. Add and edit appointments quickly!

Backup
Easy- to- use backup feature. Built- in backup reminder.

Bar Coding
Works with most bar code scanners. Print out your own bar code labels.

Cash Drawer
Works with commercially available cash drawers.

Client Tracking
Record all information about your clients, including notes and treatment history, pictures, products, products bought, total spent, and much more.

Credit Cards
Select from two choices on how to process credit cards.

Employees
Determine employee performance including percent retained, top clients, and top clients for each employee.

General Ledger
Track the financial transactions of your business, such as rent payments, utility payments, vendor shipments, and written checks. The General Ledger works very much like an interactive bank account statement. It even allows immediate check printing!

Gift Cards
Gift cards provide a quick and efficient way for your clients to pre-pay for products and services.

Gift Certificates
Keep a record of all gift certificates, original amount, and current balances.

Help System
Built- in help file and documentation.

Importing
Import client, employee, product, service, and vendor information from an existing database.

Inventory
Automatically organize, count, track, tally, and order inventory based on your specification.

Mailing
Create automatic mailing lists and labels that can be printed directly to gum labels, and work with other programs that do mail merging. Orchid Medical Spa Software comes with over 37 built in gum label formats.

Networking
Connect multiple computers together within the same building and easily share information. Wide Area networking (linking together multiple locations) is coming soon.

Online Booking
Your business can have its own, customized web site and your clients can book appointments and view your business's information (services offered, specials, etc.) over the internet.

Package Support
Products and services can be easily grouped together and added to sales transaction in one step.

Passwords
Keep your information secure with complete and versatile password protection. A master password allows access to every screen, and a separate password can be set for each individual screen.

Payroll
Calculate payroll based on your specifications including local, state, federal, retirement, health care, and end of month or year totals. Percent Retained Determine the percent of customers each employee and your medical spa retains with GREAT flexibility in search criteria.

PDA
Use a Pocket PC, or Personal Data Assistant, to download appointments and carry with you.

Pictures
Record pictures of clients, including before and after sets, with a digital camera or scanner.

Profit and Loss
The Professional and Networking packages of Orchid Medical Spa Software can produce a complete profit and loss report.

Products
Track all product information, including retail and wholesale prices, stock count, and automatic reorder points.
QuickBooks Compatibility
Financial transactions, client , product, service, employee, and vendor information can easily be exported to QuickBooks.

Reports
Orchid Medical Spa Software includes over two hundred built- in reports and the ability to create your own reports.

Sales
Track and schedule appointments (even recurring) for services and products purchased.

Scheduling
Enter in each employee's recurring schedule (hours worked, days, off, holidays). Works with the appointment book.

Services
Keep a completely custom list of service descriptions and prices. Orchid Medical Spa Software also 'remembers' what you charged each client for a particular service.

Time Clock
Complete built- in time clock. Record hours worked and use in payroll calculations.

Tips
Optionally enter in tips when the time clock feature is used.

Vendors
Keep a record of vendor information and payment history.

Wide Area Networking
Connect multiple stores together using our WAN (Wide Area Networking) feature.

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Just unpack & install. If you want to use Professional version unrarcrack1.rar into install dir and use any name & serial. If you want to use Network edition then use crack2.rar